Genetic disease

Last Friday my wife donated a kidney to me. I had(!) end stage renal disease caused by polycystic kidney disease. PKD is an autosomal dominate genetic defect affecting each fetus of a victim at rate of 50%. Each of mine have a 50-50 chance of PKD. Questions: 1- any genetic disease in your Parker line? 2-What disease?3) If yes, what is your Parker Family Project yDNA Family Group #? Me , 1- maybe, gg-gf, Cicero Parker(1949-1915)died of Bright's Disease, a catch all name for renal failure. No other cases. 2) PKD 3) #7 We are recuperating at our daughter's home. Lots of think to think. Michael R. Parker, parkerheritage.com

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  • Hi Mike, My Parker Family is plagued with Autoimmune Diseases. I developed Graves Disease two years ago at the age of 59. I later found out that a 1st cousin once removed who was much older and has since passed away, also developed Graves Disease later on in life. My Aunts Granddaughter who is in her late 20's also has Graves Disease.
    Another Aunt who has since passed developed Lupus in her 30's. A sister to this Aunt had a daughter who also had Lupus and died in her 40's. My sister fortunately has a mild case of Lupus and is doing well.
    A first cousin of mine has Vitiligo, which is related to Graves, Lupus, and other Autoimmune Diseases.
    Parker Family Project Y-DNA Family Group # 42.
  • Mike, one more thought. If you do not hear from Ranell Parker, widow of Tally Parker of Fort Worth, Texas, please know he also had Type 2 diabetes with complications of heart trouble. Tally Parker was P91.

    Patricia Ross Parker
  • Hi Mike - Glad to know that things are improving for you. I do not know if my Jack P11's Type 2 Diabetes is considered a genetic disease, only that the predisposition for it to develop is inherited. Jack's father died of complications from Type 2 at age 52. Since Jack is now 83, he is grateful that science has improved treatments for management..
    Patricia Ross Parker.
  • Michael, there is one mutation in mine but not sure what it is. My Grandson has SMA, Spinal Muscular Atrophy, but don't know if it is from my line or ex wife?
  • Time to think-brain fog
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